19-O-Acetylchaetoglobosin A

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	570.7

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

19-O-Acetylchaetoglobosin A 是一种细胞松弛素生物碱，是一种真菌代谢物，最初是从 C. globosum 中分离出来的，具有肌动蛋白聚合抑制和细胞毒活性。 19-O-Acetylchaetoglobosin A 对 HeLa 宫颈癌细胞具有细胞毒性。
货号:ajcx24014
CAS:50939-69-0
分子式:C34H38N2O6
分子量：570.7
溶解度:
纯度：98%
存储：Store at -20°C
库存：现货

Background:

19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.^1,2It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 µM.²19-O-Acetylchaetoglobosin A (3.2, 10, and 32 µg/ml) is cytotoxic to HeLa cervical cancer cells.¹

1.Umeda, M., Ohtsubo, K., Saito, M., et al.Cytotoxicity of new cytochalasans from Chaetomium globosumExperientia31(4)435-438(1975) 2.Sekita, S., Yoshihira, K., Natori, S., et al.Structure-activity relationship of thirty-nine cytochalasans observed in the effects on cellular structures and cellular events and on actin polymerization in vitroJ. Pharmacobiodyn.8(11)906-916(1985)