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Aselacin C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aselacin C图片
规格:98%
分子量:907.1
包装与价格:
包装价格(元)
100ug电议
500ug电议

产品介绍
A cyclic pentapeptolide antagonist of ETA and ETB
货号:ajcx23880
CAS:156223-08-4
分子式:C46H66N8O11
分子量:907.1
溶解度:
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Aselacin C is a cyclic pentapeptolide antagonist of endothelin receptor type A (ETA) and ETBoriginally isolated fromAcremonium.1It inhibits the binding of endothelin-1 to isolated bovine atrial membranes and porcine cerebral membranes, which endogenously express high levels of ETAand ETB, respectively, with IC50values of 60 and 80 µg/ml, respectively.


1.Jackson, M., Burres, N.S., Karwowski, J.P., et al.Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activityJ. Antibiot.47(5)523-527(1994)