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Trospium-d8(chloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Trospium-d8(chloride)图片
规格:98%
分子量:436
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx23670
CAS:N/A
分子式:C25H22D8NO3.Cl
分子量:436
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Trospium-d8is intended for use as an internal standard for the quantification of trospium by GC- or LC-MS. Trospium is an antagonist of muscarinic (M) receptors (Kis = 0.50-2.3 nM for human M1-5recombinant receptors, respectively).1Formulations containing antimuscarinics, including trospium, are used to manage overactive bladder by relieving urgency, frequency, and incontinence.1,2,3


1.Hegde, S.S.Muscarinic receptors in the bladder: From basic research to therapeuticsBr. J. Pharmacol.147(2)S80-S87(2006) 2.Maggiore, U.L.R., Salvatore, S., Alessandri, F., et al.Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in femalesExpert Opin.Drug Metab.Toxicol.8(11)1387-1408(2012) 3.Michel, M.C., and de la Rosette, J.J.M.C.H.Role of muscarinic receptor antagonists in urgency and nocturiaBJU Int.96(Suppl 1)37-42(2005)