A neuropeptide with diverse biological activities
货号:ajcx22966
CAS:N/A
分子式:C25H7D15OP.Br
分子量：464.4
溶解度:DMF: 20 mg/mL,DMSO: 20 mg/mL,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL,Ethanol: 12 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MitoP-d₁₅is intended for use as an internal standard for the quantification of MitoP by GC- or LC-MS. MitoP is a phenol product produced by the reaction of H₂O₂with the ratiometric mass spectrometry probe MitoB . MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H₂O₂to produce MitoP.^1,2Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H₂O₂concentration.

1.CochemÉ, H.M., Quin, C., McQuaker, S.J., et al.Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrixCell Metabolism13(3)340-350(2011) 2.CochemÉ, H.M., Logan, A., Prime, T.A., et al.Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living DrosophilaNature Protocols7(5)946-958(2012)