An internal standard for the quantification of carnitine
货号:ajcx22320
CAS:1219386-75-0
分子式:C7H7D9NO3.Cl
分子量：206.7
溶解度:DMF: 15 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DL-Carnitine-d₉is intended for use as an internal standard for the quantification of carnitine by GC- or LC-MS. DL-Carnitine is a racemic mixture of L- and D-carnitine. Unlike L-carnitine, DL-carnitine (60 and 120 µM) does not increase glucose or urea production from L-glutamine in isolated rat liver and does not compensate for carnitine deficiency in the skeletal muscle of rats receiving a carnitine-deficient diet.^1,2DL-Carnitine induces tetanic fade in stimulated isolated rat phrenic nerve diaphragm preparations when used at a concentration of 60 µM, an effect that can be blocked by choline.³

1.Lopes, G., Gazola, V.A., Galende, S.B., et al.Comparative acute effects of l-carnitine and dl-carnitine on hepatic catabolism of l-alanine and l-glutamine in ratsActa Pharmacol. Sin.25(10)1257-1261(2004) 2.Spasov, A.A., Iezhitsa, I.N., Kravchenko, M.S., et al.Effects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient dietBull. Exp. Biol. Med.142(4)458-460(2006) 3.Lopes, G., Bazotte, R.B., Curi, R., et al.L- and DL-carnitine induce tetanic fade in rat neuromuscular preparationBraz. J. Med. Biol. Res.36(9)1255-1262(2003)