A neuropeptide with diverse biological activities
货号:ajcx21058
CAS:N/A
分子式:C34H35D31O4
分子量：570.1
溶解度:DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

10-PAHSA-d₃₁contains 31 deuterium atoms and is intended for use as an internal standard for the quantification of 10-PAHSA by GC- or LC-MS. 10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). 10-PAHSA is a FAHFA in which palmitic acid is esterified to 10-hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.¹As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 10-PAHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.

1.Yore, M.M., Syed, I., Moraes-Vieira, P.M., et al.Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effectsCell.159(2)318-332(2014)