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Triamcinolone acetonide-d7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Triamcinolone acetonide-d7图片
规格:98%
分子量:441.5
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
C24H24D7FO6
货号:ajcx19650
CAS:N/A
分子式:C24H24D7FO6
分子量:441.5
溶解度:Chloroform: Slightly Soluble,Methanol: Slightly Soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Triamcinolone acetonide-d7 is intended for use as an internal standard for the quantification of triamcinolone acetonide by GC- or LC-MS. Triamcinolone acetonide is a synthetic corticosteroid.1 It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 μl of a 40 mg/ml suspension is administered subconjunctivally.2 Formulations containing triamcinolone acetonide are used in the treatment of diabetic macular edema.

参考文献
1. Li, H., Xie, W., Strong, J.A., et al. Systemic antiinflammatory corticosteroid reduces mechanical pain behavior, sympathetic sprouting, and elevation of proinflammatory cytokines in a rat model of neuropathic pain. Anesthesiology 107(3), 469-477 (2007).
2. Kumar, S., Shah, S., Deutsch, E.R., et al. Triamcinolone acetonide decreases outflow facility in C57BL/6 mouse eyes. Invest. Ophthalmol. Vis. Sci. 54(2), 1280-1287 (2013).