Gemcitabine monophosphate is a monophosphate form of the deoxycytidine analog gemcitabine.
货号:ajcx18480
CAS:N/A
分子式:C9H10F2N3O7P•2Na [H2O]
分子量：405.2
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Gemcitabine monophosphate is a monophosphate form of the deoxycytidine analog gemcitabine . It has synergistic effects when used in nanoparticle form in combination with cisplatin nanoparticles in vitro at a one-to-one molar ratio (IC50s = 5.95, 34.8, and 15.7 &#181M for nanoparticle combination, gemcitabine monophosphate alone, and cisplatin alone, respectively). In a stroma-rich mouse xenograft model, the nanoparticle combination of gemcitabine and cisplatin inhibits tumor growth and increases apoptosis.