CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium.
货号:ajcx18232
CAS:N/A
分子式:C44H68N10O9•XCF3COOH
分子量：881.1
溶解度:DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 0.5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium. It acts as a cell-permeable inhibitor of calcium influx through glutamate receptor channels in cultured rat neocortical neurons (IC50 = 37.25 µM) thereby inhibiting excitatory cytotoxicity (IC50 = 50.97 µM) and apoptosis (IC50 = 33.41 µM).