Lofepramine is an antidepressant; serotonin and norepinephrine re-uptake inhibitor (SNRI). A psychotropic IMIPRAMINE analogue that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE. Lofepramine is a third generation tricyclic antidepressant utilized throughout Europe and Japan for the treatment of major depression. References: Lancaster SG, Gonzalez JP. Lofepramine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs. 1989 Feb;37(2):123-40. Review. PubMed PMID: 2649353.

纯度：≥98%

CAS：26786-32-3