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Ropivacaine mesylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ropivacaine mesylate图片
规格:98%
分子量:370.51
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Ropivacaine mesylate 是一种氨基酰胺化合物,有阻断神经性疼痛的作用。Ropivacaine mesylate 是一种 K2P (双孔钾通道) TREK-1 抑制剂,在 COS-7 细胞膜上其 IC50 值为 402.7 μM。Ropivacaine mesylate 能在急性高血压模型中抑制压力诱导的肺内皮细胞高通透性。
货号:ajcx17410
CAS:854056-07-8
分子式:C18H30N2O4S
分子量:370.51
溶解度:H2O: 250 mg/mL (674.75 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Ropivacaine mesylate is an aminoamide compound, effectively blocks neuropathic pain. Ropivacaine mesylate is an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine mesylate inhibits pressure-induces lung endothelial hyperpermeability in models of acute hypertension[1][2].


[1]. Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10(1):e0117321. [2]. Milan Patel, et al. Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension. Life Sci. 2019 Apr 1;222:22-28.