8pyDTZ 是一种吡啶基二苯基叔嗪 (DTZ) 类似物，也是 一种 LumiLuc 荧光素酶的 ATP 非依赖性吡啶基底物。8pyDTZ 表现出光谱偏移的发射并改善了水溶性。8pyDTZ 具有出色的生物相容性和体内敏感性，可用于生物体内发光成像。
货号:ajcx16434
CAS:2351898-91-2
分子式:C24H18N4O
分子量：378.43
溶解度:DMSO: 12.5 mg/mL (33.03 mM; DMSO can inactivate 8pyDTZ's activity); EtOH+HCl: 2 mg/mL (5.28 mM; ultrasonic and adjust pH to 2 with 1M HCl; DMSO can inactivate 8pyDTZ's activity); H2O:< 0.1 mg/mL (insoluble; DMSO can inactivate 8pyDTZ's activity)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission and improved water solubility. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging[1].

[1]. Yeh HW, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019 May 17;14(5):959-965.