您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Fluticasone furoate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Fluticasone furoate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fluticasone furoate图片
规格:98%
分子量:538.58
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
Fluticasone furoate 是一种局部,鼻内,增强亲和力的合成的三氟皮质类固醇,Kd 为 0.3 nM。Fluticasone furoate 具有有效的抗炎和抗哮喘活性,并且全身暴露率低。Fluticasone furoate 可用于过敏性鼻炎的研究。
货号:ajcx16220
CAS:397864-44-7
分子式:C27H29F3O6S
分子量:538.58
溶解度:DMSO: 250 mg/mL (464.18 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment[1][2].


[1]. Giavina-Bianchi P, et al. Fluticasone furoate nasal spray in the treatment of allergic rhinitis. Ther Clin Risk Manag. 2008 Apr;4(2):465-72. [2]. Alizadeh Z, et al. Asthma phenotypes and T-bet protein expression in cells treated with Fluticasone Furoate/Vilanterol. Pulm Pharmacol Ther. 2020 Feb;60:101886.