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Raseglurant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:757950-09-7
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
50mg电议
500mg电议

产品介绍

Raseglurant, aslo known as ADX-10059, is a negative allosteric modulator of the mGlu5 receptor and analogue of MPEP which was under development by Addex Therapeutics for the treatment of migraine, gastroesophageal reflux disease, and dental anxiety. It reached phase II clinical trials for all of the aforementioned indications before being discontinued due to the observation of possible predictive signs of hepatotoxicity in patients with long-term use. References: Marin JC, Goadsby PJ. Glutamatergic fine tuning with ADX-10059: a novel therapeutic approach for migraine? Expert Opin Investig Drugs. 2010 Apr;19(4):555-61. doi: 10.1517/13543781003691832. Review. PubMed PMID: 20218930.

纯度:≥98%

CAS:757950-09-7