规格: | 98% |
分子量: | 623.68 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
Background:
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations[1]. FPR/FPRL1[1]
Boc-MLF inhibits superoxide production induced by FPR agonist fMLF, with an EC50 of 630 nM in neutrophils[1].Boc-MLF (25 μM) blocks FPRL1-agonist serum amyloid A (SAA) induced calcium response[1].
[1]. Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9. Epub 2007 Aug 9.