CMD178是一种重要的多肽，能够持续地通过抑制IL-2/sIL-2Rα信号通路来减少Foxp3和STAT5的表达。CMD178是STAT5的抑制剂,并可抑制Treg细胞的发育。
货号:ajcx13212
CAS:N/A
分子式:C46H59N9O7
分子量：850.03
溶解度:Soluble in H2O
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling. CMD178 also is an inhibitor of STAT5 and inhibit Treg cell development[1].

[1]. Price-Troska T, et al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2018 Apr 26.