| 规格: | 98% |
| 分子量: | 491.56 |
| 包装 | 价格(元) |
| 250mg | 电议 |
| 500mg | 电议 |
Background:
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity. AZD7624 inhibits LPS-induced TNFα in human mononuclear cells, in whole blood as well as in alveolar macrophages in vitro, with pIC50u of 8.4, 8.7, and 9.0[1].
[1]. Pehrson R, et al. AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure. J Pharmacol Exp Ther. 2018 Jun;365(3):567-572.
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