GNE-0946是一个有效且有选择性的RORγ(RORc)拮抗剂，对HEK-293细胞的EC50值为4nM.
货号:ajcx12662
CAS:1677667-24-1
分子式:C22H12ClF3N2O4
分子量：460.79
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell.

[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.