Elobixibat是有效的ilealbileacidtransporter(IBAT)抑制剂,IC50值分别为0.53±0.17nM(人类IBAT),0.13±0.03nM(小鼠IBAT),5.8±1.6nM(犬类IBAT)。
货号:ajcx12610
CAS:439087-18-0
分子式:C36H45N3O7S2
分子量:695.89
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Elobixibat is a potent ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT.
[1]. Wong BS, et al. Elobixibat for the treatment of constipation. Expert Opin Investig Drugs. 2013 Feb; 22(2):277-84.