Description: Lobeline (+)-, an isomer of lobeline which is an alkaloid and nonstimulant medication that can alter dopamine uptake in brain, is a novel and potent a nicotinic receptor agonist and VMAT2 ligand, which stimulates dopamine release, and inhibits the reuptake of dopamine and serotonin, acting as a mixed agonist-antagonist at nicotinic acetylcholine receptors and antagonist at μ-opioid receptors.

References: Nickell JR, Siripurapu KB, Horton DB, Zheng G, Crooks PA, Dwoskin LP. GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2. Eur J Pharmacol. 2017 Jan 15;795:143-149.

Related CAS: 134-63-4 (HCl); 90-69-7 (free); 246018-80-4 (Lobeline, (+)-); 134-64-5 (sulfate)

纯度：≥98%

CAS：246018-80-4