Eculizumab (Anti-Human C5, Humanized Antibody) 是一种针对补体 C5 (complement C5) 的长效人源化单克隆抗体。Eculizumab 抑制 C5 裂解为 C5a 和 C5b，因此抑制末端补体系统的部署，包括膜攻击复合物 (MAC) 的形成。Eculizumab 具有用于溶血研究的潜力。
货号:ajcx38312
CAS:219685-50-4
分子式:N/A
分子量：N/A
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research[1].

[1]. Eline A Dubois,et al. Eculizumab. Br J Clin Pharmacol. 2009 Sep;68(3):318-9.