N-CBZ-Phe-Arg-AMC (Z-FR-AMC) TFA 是一种组织蛋白酶底物,可用于评估溶酶体组织蛋白酶的活性。
货号:ajcx38062
CAS:N/A
分子式:C35H37F3N6O8
分子量:726.7
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) TFA is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].
[1]. Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):246-53.
[2]. Porter K,et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013 Apr;9(4):581-94.