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7-Hydroxyflavone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-Hydroxyflavone图片
规格:98%
分子量:238.24
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
7-Hydroxyflavone 是从 M. indica 中分离出的一种黄酮类化合物,具有抗炎作用。7-Hydroxyflavone 能通过 ERK/Nrf2/HO-1 通路保护肾细胞免受尼古丁 (NIC) 诱导的细胞毒性。
货号:ajcx36070
CAS:6665-86-7
分子式:C15H10O3
分子量:238.24
溶解度:DMSO : 125 mg/mL (524.68 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

7-Hydroxyflavone is a flavonoid isolated from M. indica, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway[1][2].

[1]. Vinutha K, et al. Aqueous extract from Madhuca indica bark protects cells from oxidative stress caused by electron beam radiation: in vitro, in vivo and in silico approach. Heliyon. 2019 May 30;5(5):e01749.
[2]. Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777.
[3]. Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777.