DebutyldronedaroneD6hydrochloride(SR35021D6hydrochloride)是Debutyldronedarone的氘代物。Debutyldronedarone是Dronedarone在人体中的主要循环活性代谢物(metabolite)。Debutyldronedarone的效力是Dronedarone的1/10到1/3。
货号:ajcx30474
CAS:1346598-70-6
分子式:C27H31D6ClN2O5S
分子量：543.15
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].

[1]. Cen Xie, et al. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.J Chromatogr B Analyt Technol Biomed Life Sci [2]. Marina Santos, et al.Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride. J Pharm Biomed Anal. 2015 Oct 10;114:441-6.