8-DemethylIvabradine是Ivabradine的一个代谢物。Ivabradine是具有口服活性的,超极化激活的环核苷酸门控离子通道(HCN)通道阻滞剂。
货号:ajcx30078
CAS:304464-97-9
分子式:C26H34N2O5
分子量:454.56
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
8-Demethyl Ivabradine is a metabolite of Ivabradine. Ivabradine is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker[1].
[1]. M FranÇois-Bouchard,et al. Simultaneous determination of ivabradine and its metabolites in human plasma by liquid chromatography--tandem mass spectrometry. J Chromatogr B Biomed Sci Appl. 2000 Aug 18;745(2):261-9.