4-Hydroxyderricin是当归的主要活性成分之一，是一种有效的，选择性MAO-B(单胺氧化酶抑制剂)抑制剂，IC50为3.43μM。4-Hydroxyderricin可以轻度抑制DBH(多巴胺β-羟化酶)活性。4-Hydroxyderricin具有抗抑郁活性。
货号:ajcx30036
CAS:55912-03-3
分子式:C21H22O4
分子量：338.4
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].

[1]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.