规格: | 98% |
分子量: | 249.35 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
Background:
Desmethylnortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
[1]. Burch JE, et al. Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde. J Chromatogr. 1983 May 13;274:350-4. [2]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.