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5-Hydroxytoluene-2,4-disulphonic acid diammonium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-Hydroxytoluene-2,4-disulphonic acid diammonium图片
规格:98%
分子量:302.33
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
5-Hydroxytoluene-2,4-disulphonicaciddiammonium是Policresulen的杂质。Policresulen是一种有效的NS2B/NS3蛋白酶抑制剂,IC50为0.48μg/mL。Policresulen有效抑制DENV2病毒在BHK-21细胞中的复制,IC50为4.99μg/mL。Policresulen是蛋白酶的竞争性抑制剂,并轻微影响蛋白酶的稳定性。
货号:ajcx29076
CAS:N/A
分子式:C7H14N2O7S2
分子量:302.33
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

5-Hydroxytoluene-2,4-disulphonic acid diammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].


[1]. Deng-wei Wu, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015 Sep;36(9):1126-36.