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RGD Peptide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RGD Peptide图片
规格:98%
分子量:614.6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
An inhibitor of integrin-ligand interactions
货号:ajcx28564
CAS:114681-65-1
分子式:C23H38N10O10
分子量:614.6
溶解度:DMF: 14 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 0.33 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

RGD peptide is a synthetic compound made up of the arginine-glycine-aspartate motif that has been extensively used to inhibit integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.1RGD peptide has also been shown to directly induce apoptosis, independent of integrin-mediated cell clustering or signals, by initiating conformational changes that enhance pro-caspase-3 activation and autoprocessing.2,3

1.Ruoslahti, E., and Öbrink, B.Common principles in cell adhesionExp. Cell Res.2271-11(1996) 2.Buckley, C.D., Pilling, D., Henriquez, N.V., et al.RGD peptides induce apoptosis by direct caspase-3 activationNature397534-539(1999) 3.Adderley, S.R., and Fitzgerald, D.J.Glycoprotein IIb/IIIa antagonists induce apoptosis in rat cardiomyocytes by caspase-3 activationJ. Biol. Chem.2755760-5766(2000)