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5-hydroxy Isatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-hydroxy Isatin图片
规格:98%
分子量:163.1
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
An inhibitor of MAO-A
货号:ajcx28392
CAS:116569-09-6
分子式:C8H5NO3
分子量:163.1
溶解度:DMF: 3 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
纯度:98%
存储:Store at -20°C
库存:现货

Background:

5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50= 8.4 µM).1It is selective for MAO-A over MAO-B (IC50= >100 µM). 5-hydroxy Isatin (50 µM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2

1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992) 2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999)