C48H50BrF2N9O8
货号:ajcx28152
CAS:N/A
分子式:C48H50BrF2N9O8
分子量：998.87
溶解度:DMSO|99.89|100|
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent and selective p38α and p38β degrader (DC50 < 50 nM). Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2. Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-derived macrophages (BMDM). Exhibits similar effect to p38α gene knockout in BBL358 cells. Active in vivo.