An RORγt antagonist
货号:ajcx28090
CAS:1334526-14-5
分子式:C25H31NO6
分子量：441.52
溶解度:DMSO: 100 mM
纯度：98%
存储：Store at -20°C
库存：现货

Background:

RORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).