C16H19F3N4O2.HCl
货号:ajcx27992
CAS:1422252-46-7
分子式:C16H19F3N4O2.HCl
分子量：392.8
溶解度:DMSO|19.64|50|
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent and selective NHE1 inhibitor (IC50 = 31 nM). Selective for NHE1 over NHE2 and NHE3. Prevents ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo. Prevents phenylephrine-induced cardiomyocyte hypertrophy in vitro, and attenuates cardiac hypertrophy and left ventricular dysfunction postinfarction in rats. Orally bioavailable.