PAMP-12（人、猪）是免疫反应性 (ir)-PAMP 的主要成分，由肾上腺髓质素前体加工而成，是一种有效的降血压肽，参与心血管控制。
货号:ajcx27674
CAS:196305-05-2
分子式:C77H119N25O14
分子量：1618.95
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.

Kamohara et al (2005) Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides. Biochem.Biophys.Res.Commun. 330 1146 PMID:15823563 |Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 13 529 PMID:28288109