CIM 0216 是一种合成的 TRPM3 配体,是一种有效的选择性 TRPM3 激动剂。
货号:ajcx27088
CAS:1031496-06-6
分子式:C21H21N3O2
分子量:347.41
溶解度:DMSO: slightly soluble,Methanol: slightly soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Selective TRPM3 agonist. Exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. Stimulates insulin release from pancreatic islet cells in vitro. Evokes nocifensive behavior in mice.
Held et al (2015) Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. Proc.Natl.Acad.Sci.U.S.A. 112 E1363 PMID:25733887