6bK 是一种有效的选择性胰岛素降解酶 (IDE) 抑制剂,IC50 值为 50 nM。
货号:ajcx27032
CAS:1417537-93-9
分子式:C41H55N7O7
分子量:757.92
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Insulin degrading enzyme (IDE) inhibitor (IC50 = 50 nM); regulates insulin, glucagon and amylin levels, and improves glucose tolerance in a diabetic mouse model. This compound is supplied in net weight as the TFA salt.
Maianti et al (2014) Anti-diabetic activity of Ins-degrading enzyme inhibitors mediated by multiple hormones. Nature 511 94 PMID:24847884