A glucose derivative with anticancer activity
货号:ajcx24882
CAS:29702-43-0
分子式:C6H11FO5
分子量:182.1
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
2-deoxy-2-fluoro-D-Glucose (2-FG) is a derivative of glucose with anticancer activity.1It inhibits the growth of 143B osteosarcoma cells grown under normoxic and hypoxic conditions when used at concentrations of 6 and 24 mM.
1.Lampidis, T.J., Kurtoglu, M., Maher, J.C., et al.Efficacy of 2-halogen substituted ?-glucose analogs in blocking glycolysis and killing ''hypoxic tumor cells''Cancer Chemother. Pharmacol.58(6)725-734(2006)