Background:

Pentalenic acid is a sesquiterpenoid that has been found inS. avermitilis.¹It is a precursor in the biosynthesis of the antibiotic pentalenolactone.

1.Takamatsu, S., Xu, L.-H., Fushinobu, S., et al.Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: Hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilisJ. Antibiot.64(1)65-71(2011)