Background:

Bassianin is a fungal metabolite that has been found inBeauveria.^1,2It inhibits Mg²⁺-, Ca²⁺-, and Na⁺/K⁺-ATPase activities in equine erythrocyte ghosts by 81, 58, and 23%, respectively, when used at a concentration of 200 µg/ml.¹Bassianin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC₅₀) values of 4.91 and 12.12 µM, respectively.²

1.Jeffs, L.B., and Khachatourians, G.G.Toxic properties of Beauveria pigments on erythrocyte membranesToxicon.35(8)1351-1356(1997) 2.Arboleda Valencia, J.W., GaitÁn Bustamante, A.L., JimÉnez, A.V., et al.Cytotoxic activity of fungal metabolites from the pathogenic fungus Beauveria bassiana: An intraspecific evaluation of beauvericin productionCurr. Microbiol.63(3)306-312(2011)