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Nafcillin-d5(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nafcillin-d5(sodium salt)图片
包装:1mg
规格:98%
市场价:1482元
分子量:441.5

产品介绍
An internal standard for the quantification of nafcillin
货号:ajcx24198
CAS:1356354-25-0
分子式:C21H16D5N2O5S•Na
分子量:441.5
溶解度:DMSO: slightly soluble,Methanol: slightly soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Nafcillin-d5is intended for use as an internal standard for the quantification of nafcillin by GC- or LC-MS. Nafcillin is a semisynthetic and penicillinase-resistant penicillin antibiotic.1It is active against 20 clinical isolates ofS. aureuswith minimum bactericidal concentration (MBC) values ranging from 0.078 to 0.312 µg/ml. Nafcillin (100-800 mg/kg) reduces the number of kidney colony forming units (CFUs) in a mouse model ofS. aureusinfection.2It also reduces the number of right atrial CFUs in a rabbit model ofS. aureus-induced endocarditis.3Formulations containing nafcillin have been used in the treatment of various bacterial infections.


1.Tuazon, C.U., Lin, M.Y., and Sheagren, J.N.In vitro activity of rifampin alone and in combination with nafcillin and vancomycin against pathogenic strains of Staphylococcus aureusAntimicrob. Agents Chemother.13(5)759-761(1978) 2.Yuchenco, J.A., Hopper, M.W., Vince, T.D., et al.Nafcillin and oxacillin: Comparative antistaphylococcal activity in miceJ. Antibiot. (Tokyo)29(4)460-465(1976) 3.Carrizosa, J., Kobasa, W.D., and Kaye, D.Effectiveness of nafcillin, methicillin, and cephalothin in experimental Staphylococcus aureus endocarditisAntimicrob. Agents Chemother.15(5)735-737(1979)