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MPro Inhibitor 11b
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MPro Inhibitor 11b图片
规格:98%
分子量:464.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An inhibitor of SARS-CoV-2 Mpro
货号:ajcx22998
CAS:2413716-71-7
分子式:C25H25FN4O4
分子量:464.5
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 µM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.72 µM). MProinhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 µM.


1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main proteaseScience368(6497)1331-1335(2020)