A neuropeptide with diverse biological activities
货号:ajcx22186
CAS:N/A
分子式:C63H88N16O14S.XCF3COOH
分子量：1325.5
溶解度:Formic Acid: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH₂is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-2, MMP-3, and MMP-9.¹Upon enzymatic cleavage by MMP-1, MMP-2, MMP-3, or MMP-9 at the Gly-Leu site, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify MMP-1, MMP-2, MMP-3, and MMP-9 activity.^1,2EDANS displays excitation/emission maxima of 340/485 nm, respectively.

1.Beekman, B., Drijfhout, J.W., Bloemhoff, W., et al.Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological mediaFEBS Lett.390(2)221-225(1996) 2.Krismastuti, F.S.H., Pace, S., and Voelcker, N.H.Porous silicon resonant microcavity biosensor for matrix metalloproteinase detectionAdv. Funct. Mater.24(23)3639-3650(2014)