包装: | 100mg |
规格: | 98% |
市场价: | 374元 |
分子量: | 192 |
Background:
Clopyralid is an herbicide that selectively inhibits the growth of the broadleaf weedL. palustrisover a panel of 17 New Zealand native non-broadleaf plant species when applied at a concentration of 1.5 mg/L.1It does not inhibit growth of human pluripotent stem cells (IC50= >100 μM) or decrease nuclear translocation of the transcription factor SOX17, a marker of teratogenic risk.2In vivo, clopyralid induces brain defects in rabbits, but not rats, when administered at a dose of 250 mg/kg.
1.Champion, P.D.Selective control of weeds in New Zealand wetlandsProceedings of the 51st New Zealand Plant Protection Conference251-254(1998) 2.Kameoka, S., Babiarz, J., Kolaja, K., et al.A high-throughput screen for teratogens using human pluripotent stem cellsToxicol. Sci.137(1)76-90(2014)