A neuropeptide with diverse biological activities
货号:ajcx21218
CAS:N/A
分子式:C18H21D9O5
分子量：335.5
溶解度:DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

2,3-dinor-11β-Prostaglandin F_2α-d₉(2,3-dinor-11β-PGF_2α-d₉) is intended for use as an internal standard for the quantification of 2,3-dinor-11β-PGF_2αby GC- or LC-MS. 2,3-dinor-11β-PG_2αwas recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD₂, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively.¹2,3-dinor-11β-PGF_2αhas also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts.²In human asthmatic patients, 2,3-dinor-11β-PGF_2αrepresents about 40% (as determined by GC-MS) of the immunoreactive 11β-PGF_2αwhen measured using 's 11β-PGF_2αEIA Kit . The excretion rate for 2,3-dinor-11β-PGF_2αis approximately 200-250 ng/24 hours in a normal adult.³

1.Liston, T.E., and Roberts, L.J., IIMetabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteerJ. Biol. Chem.260(24)13172-13180(1985) 2.Roberts, L.J., II, and Sweetman, B.J.Metabolic fate of endogenously synthesized prostaglandin D2 in a human female with mastocytosisProstaglandins30(3)383-400(1985) 3.O'Sullivan, S., Mueller, M.J., DahlÉn, S.E., et al.Analyses of prostaglandin D2 metabolites in urine: Comparison between enzyme immunoassay and negative ion chemical ionization gas chromatography-mass spectrometryProstaglandins Other Lipid Mediat.57(2-3)149-165(1999)