规格: | 98% |
分子量: | 323.5 |
包装 | 价格(元) |
25ug | 电议 |
50ug | 电议 |
100ug | 电议 |
Background:
15(S)-HEPE-d5is intended for use as an internal standard for the quantification of 15(S)-HEPE by GC- or LC-MS. 15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO).1,2Serum levels of 15(S)-HEPE are elevated in patients with asthma.3
1.Miller, C., Yamaguchi, R.Y., and Ziboh, V.A.Guinea pig epidermis generates putative anti-inflammatory metabolites from fish oil polyunsaturated fatty acidsLipids24(12)998-1003(1989) 2.Tan, L., Xin, X., Zhai, L., et al.Drosophila fed ARA and EPA yields eicosanoids, 15S-hydroxy-5Z,8Z, 11Z, 13E-eicosatetraenoic acid, and 15S-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acidLipids51(4)435-449(2016) 3.Bian, X., Sun, B., Zheng, P., et al.Derivatization enhanced separation and sensitivity of long chain-free fatty acids: Application to asthma using targeted and non-targeted liquid chromatography-mass spectrometry approachAnal. Chim. Acta.98959-70(2017)