An acylhydrazone antifungal
货号:ajcx20584
CAS:321945-27-1
分子式:C14H9Br3N2O2
分子量:476.9
溶解度:DMF: 30 mg/ml,DMSO: 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.
|1. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrob. Agents Chemother. 62(5), e00156-00118 (2018).