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Angiotensin II(3-8)(human,rat,mouse)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Angiotensin II(3-8)(human,rat,mouse)(trifluoroacetate salt)图片
包装:1mg
规格:98%
市场价:1122元
分子量:774.9

产品介绍
Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.
货号:ajcx18100
CAS:N/A
分子式:C40H54N8O8•XCF3COOH
分子量:774.9
溶解度:Water: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II . It selectively binds to the angiotensin 2 (AT2) over AT1 receptors (IC50s = 48.6 and >1,000 nM, respectively, in HEK293 cells expressing rat receptors). It also binds to AT4 receptors in bovine aortic endothelial cell membranes (IC50 = 1.6 nM). Angiotensin II (3-8) induces a positive chronotropic effect in isolated rat right atria (EC50 = 4.68 μM) and increases mean arterial pressure (MAP) in vivo in rats when administrated intracerebroventricularly at a dose of 1 pmol. It also increases latency to withdrawal in a tail-flick test in rats when administered by microinjection into the ventrolateral periaqueductal gray (vlPAG).