Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively).
货号:ajcx17488
CAS:N/A
分子式:C22H36N4O10 • XCF3COOH
分子量：516.5
溶解度:DMSO: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively). Boc-AEVD-CHO has been used to study the potential interference of caspase-8 activity in micronuclei detection. It inhibits apoptosis induced by the aneugen nocodazole in isolated human peripheral blood mononuclear cells (PBMCs) when used at a concentration of 300 µM.