CC-92480 是一种cereblon E3 泛素连接酶调节药物 (CELMoD)。CC-92480 与cereblon 有较强的亲和力,具有抗骨髓瘤活性。
货号:ajcx16114
CAS:2259648-80-9
分子式:C32H30FN5O4
分子量:567.61
溶解度:DMSO: 5 mg/mL (8.81 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity[1].
[1]. Nooka AK, et al. Mechanism of Action and Novel IMiD-Based Compounds and Combinations in Multiple Myeloma. Cancer J. 2019 Jan/Feb;25(1):19-31.