SCD1 inhibitor-4 是一种有效的、具有口服活性的硬脂酰辅酶A 去饱和酶-1 (SCD1) 抑制剂。
货号:ajcx12112
CAS:1295541-87-5
分子式:C??H??F?N?O
分子量:363.34
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
CD1 inhibitor-4 is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
SCD1 inhibitor-4 (1~30 mg/kg) shows a dose-dependent decrease in desaturation index with a 55 % reduction at 1 mg/kg and 85% reduction at the 10 and 30 mg/kg doses
[1].?Atkinson KA, et al. N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors. Bioorg Med Chem Lett. 2011;21(6):1621-1625.